NSU (Non-specific urethritis) is a term for inflammation of the urethra (wee-pipe) of the penis when the cause isn’t known.

NSU has many causes – some are sexually transmitted, some are not. In up to 30% of people with NSU, Chlamydia will be the cause.

Other sexually transmitted infection causes of NSU include Trichomonas, Herpes and Mycoplasma. NSU symptoms can also be caused by other organisms which are not sexually transmitted. Friction (during sex or masturbation) and sensitivity to chemicals such as spermicide, soap or latex can also give irritation or inflammation in the urethra.

You might notice irritation or itching in the wee pipe, discomfort or pain when peeing, or a discharge at the tip of the penis.

It is diagnosed in a sexual health clinic. A sample will be taken with a small swab from the tip of your penis. This is then looked at under a microscope.

You can use the Service Finder below to find a testing service near you.

You will be given antibiotics to treat possible chlamydia infection as this is the most common cause. If your Chlamydia test comes back negative, and your symptoms do not improve, you should return to the clinic and you may need more tests or treatment.

NSU may be sexually transmitted. If you are treated for NSU, you will need to not have sex for 7 days. Sexual contacts should also be tested and treated.

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